Having a comprehensive understanding of a drug medication you intend to use is one step closer to achieving your desired goal. As a bodybuilder, understanding Exemestane is all you need to achieve that bulging mass of lean muscle or pepping up your athletic performance for all to view with satisfaction. In this article we will discuss the effects of Exemestane and the way it works in bodybuilding. Read and enjoy!
What exactly is Exemestane?
There’s widespread medical consensus and acceptance that Exemestane 150 (Aromasin) belongs to the class off drug medications that are known as aromatase inhibitors.
Normally, this class of drug medication is used mainly for the treatment of breast cancer in postmenopausal women but bodybuilders also take it during their steroid cycles and as a supplement for their post cycle therapy (PCT).
Its popularity in sports has gained momentum especially in bodybuilding due to the need to suppress the estrogenic side effects of steroids (AAS). It’s also known by its brand name of Aromasin when it was patented by Upjohn, who also created it.
Its appearance on the American market on the eve of the 21st century marked the very first time that an anti-estrogen drug had made an entry as soon as it was given the green light to enter and compete on the market.
The work mechanism of Exemestane is similar to other popular aromatase inhibitors such as letrozole and anastrozole but the former two are not used in bodybuilding after a steroid cycle like exemestane.
Positive effects of exemestane 250
One positive effect of exemestane is that of effectively blocking the enzyme aromatase which is responsible for converting the testosterone male hormone into female hormones.
This conversion decreases the concentration of estrogen in the blood which makes the drug a perfect combatant against breast cancer which survives on the growth of estrogen levels.
This is the same reason why exemestane gained popularity among athletes who are in the habit of taking steroids.
Negative effects
One feature of AAS is that they are able to aromatize which causes some side effects, for instance, the retention of a large amount of water and the development of gynecomastia.
Gynecomastia constitutes the most serious negative effect of Aromasin but it doesn’t stop there since the retention of a large amount of water in the body can also cause high blood pressure.
Also keep in mind that non-aromatic AAS can also result in estrogenic side effects especially if they also show progestogenic activity.
One example of non-aromatic AAS is nandrolone esters which weakly interacts with aromatase (only 20 percent of testosterone), but it also possesses high progestogenic attributes.
Progestogenic attributes
Many studies have pointed out that increases in progesterone levels can lead to the unwanted development of gynecomastia.
However, using exemestane in bodybuilding while on a course of steroids can enable an athlete to erase the risks of side effects which can emerge.
Research has shown that aromasin is able to reduce the estradiol level in the blood by 85 percent which is very high and hence one of the many reasons why this drug medication has gained widespread popularity among bodybuilders.
The truth of the matter is that using exemestane for bodybuilding following a course of steroids can boost the secretion of endogenous male hormone, more popularly known as testosterone.
As a matter of fact, some athletes are already doing this with known inhibitors such as PKT but is should be known that letrozole and anastrozole have the same effect.
But exemestane has the edge
It’s widely believed that exemestane has the advantage over these other inhibitors, the reasons being that:
- The inhibitor drug has a low androgenic activity
- It speeds up the secretion of insulin-like growth factor.
It’s known that no other aromatase inhibitors possess such properties and this is the reason why when using exemestane in bodybuilding following a course of taking steroids, a bodybuilder or athlete not only restores the processes of testosterone synthesis, but also shifts the balance between anabolism and catabolism towards the first by increasing the concentration of the insulin-like growth factor.
Some bodybuilders believe that this in turn positively effects the restoration of the body simply because the rollback effect is reduced to a minimum and the muscle tissues are guarded from irreparable damage.
Summarizing only the positive effects of exemestane, the following highlights indicate that for bodybuilding this drug medication:
- Is the ideal drug for the prevention of gynecomastia.
- Can be an effective suppressant of female hormone levels.
- Is capable promoting the growth of anabolic background.
- Can improve muscle relief.
- Is a good way of preventing hypertension.
- Actually reduces the negative impact of estrogen on the pituitary arc.
Mechanisms of Exemestane 250 (Aromasin)
An important aspect to note about using exemestane is that when you use it for addressing a specific condition such as breast cancer, the cancer cells are deprived of the estrogen the need in order to survive and multiply and hence their growth ceases.
There’s no shadow of a doubt that aromasin is totally effective in treating breast cancer and inevitably other forms of cancer.
Nevertheless experts recommend that you should first use the drug tamoxifen and if the results are no positive, then you should start using exemestane.
It should also be noted that despite the proven efficacy of this drug medication, it’s not as widely used as for instance, as anastrozole. The reason is that Arimidex in many ways acts in a similar way to the primary aromatase inhibitor acts.
This happens not only in the treatment of breast cancer but also for the treatment of other types of cancer, but we are more interested in the mechanisms of exemestane, in its use for suppressing the bad effects of anabolic steroids.
It’s fortunate that we are already well acquainted with the properties and effects of exemestane to enable us to draw some conclusions as follows:
- It’s always important to remember that the side effects of the estrogen type steroid may not emerge.
- When we refer specifically to the estrogenic process, then the AAS used by athletes for their development must be able gtod aromatize or engage in progestogenic activity.
- While testosterone acts as the primary flavoring anabolic, testosterone derivatives can also enhance the work of estrogen as for instance happens with metandienone.
- Trenbolone and nandrolone are steroids that can cause estrogenic side effects. While the can weakly aromatize, the do have a strong progenstogenic activity.
- Trenbolone is incapable of interacting with the aromatase enzyme but the development of gynecomastia is still possible as can be seen when these drugs are used with flavored AAS which increases risks of side effects.
- Regardless of what steroid is used, exemestane is able to protect you from side effects.
Conclusion
We have once again, placed a wealth of carefully selected information at your disposal especially on the dynamic functions of the drug medication exemestane (Aromasin) and its positive effects. While the information is not entirely new, it does provide extensive insight into the different aspects of how the mechanism of the drug medication functions and how these functions impact on the situations that prevail on other drug medications. We trust that the information has proved both valuable and interesting.
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