Zycolchin (Colchicine) 0.5 Mg – 320 tablet

Colchicine Information

Pronunciation

KOL chi seen

What is this drug used for?

• It is used to treat gout attacks.

• It is used to prevent gout attacks.

• It is used to treat familial Mediterranean fever.

• It may be given to you for other reasons. Talk with the doctor.

Frequently reported side effects of this drug

• Diarrhea

• Nausea

• Vomiting

• Abdominal pain

Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:

• Infection

• Burning or numbness feeling

• Severe loss of strength and energy

• Bruising

• Bleeding

• Pale skin

• Muscle pain

• Muscle weakness

• Unable to pass urine

• Change in amount of urine passed

• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.

Medication Safety Issues

Sound-alike/look-alike issues:

Product Availability

Gloperba (0.6 mg/5 mL oral solution): FDA approved January 2019; availability anticipated mid-2019. Information pertaining to this product within the monograph is pending revision. Consult the prescribing information for additional information.

Storage and Stability

Store at 20°C to 25°C (68°F to 77°F). Protect from light and moisture.

Adverse Reactions

Central nervous system: Fatigue, headache

Endocrine & metabolic: Gout

Gastrointestinal: Abdominal cramps, abdominal pain, diarrhea, gastrointestinal disease, nausea, vomiting

Respiratory: Pharyngolaryngeal pain

Rare but important or life-threatening: Alopecia, bone marrow depression, dermatitis, disseminated intravascular coagulation, dysgeusia (Syed 2016), hepatotoxicity, hypersensitivity reaction, increased creatine phosphokinase in blood specimen, lactose intolerance, myalgia, myasthenia, oligospermia, nonthrombocytopenic purpura, rhabdomyolysis, toxic neuromuscular disease –