GLYCOMET (Glucophage)500mg 10 tabs

Metformin Information

Pronunciation

(met FOR min)

What is this drug used for?

• It is used to lower blood sugar in patients with high blood sugar (diabetes).

Frequently reported side effects of this drug

• Diarrhea

• Passing gas

• Nausea

• Vomiting

• Heartburn

• Headache

• Loss of strength and energy

Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:

• Lactic acidosis like fast breathing, fast heartbeat, abnormal heartbeat, vomiting, fatigue, shortness of breath, severe loss of strength and energy, severe dizziness, feeling cold, or muscle pain or cramps.

• Low blood sugar like dizziness, headache, fatigue, feeling weak, shaking, fast heartbeat, confusion, increased hunger, or sweating.

• Severe abdominal pain

• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.

Medication Safety Issues
Sound-alike/look-alike issues:

MetFORMIN may be confused with metroNIDAZOLE

Glucophage may be confused with Glucotrol, Glutofac

International issues:

Dianben [Spain] may be confused with Diovan brand name for valsartan [US, Canada, and multiple international markets].

Glucon brand name for metformin [Malaysia, Singapore] is also the brand name for glucosamine [Singapore]

Product Availability

Riomet ER 500 mg/5 mL oral suspension: FDA approved August 2019; anticipated availability is currently unknown. Information pertaining to this product within the monograph is pending revision. Consult the prescribing information for additional information.

Storage and Stability

Oral solution (immediate release): Store at 15°C to 30°C (59°F to 86°F).

Oral suspension (extended release): Store at 20°C to 25°C (68°F to 77°F); excursion permitted to 15°C to 30°C (59°F to 86°F). Discard unused portion of reconstituted suspension after 100 days.

Tablets: Store at 20°C to 25°C (68°F to 77°F); excursion permitted to 15°C to 30°C (59°F to 86°F). Protect from light and moisture.

Adverse Reactions

Cardiovascular: Chest discomfort, flushing, palpitations

Central nervous system: Chills, dizziness, headache, taste disorder

Dermatologic: Diaphoresis, nail disease, skin rash

Endocrine & metabolic: Decreased vitamin B₁₂ serum concentrate, hypoglycemia

Gastrointestinal: Abdominal distention, abdominal distress, abdominal pain, abnormal stools, constipation, diarrhea, dyspepsia, flatulence, heartburn, nausea, nausea and vomiting

Infection: Infection

Neuromuscular & skeletal: Myalgia, weakness

Respiratory: Dyspnea, flu-like symptoms, rhinitis, upper respiratory tract infection

Miscellaneous: Accidental injury

Rare but important or life-threatening: Hepatic injury (cholestatic, hepatocellular, and mixed), lactic acidosis –