Medication Safety Issues
Sound-alike/look-alike issues:
Rapaflo may be confused with Rapamune
Silodosin may be confused with sildenafil, sirolimus
Storage/Stability
Store at room temperature of 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from light. Protect from moisture.
Adverse Reactions
>10%: Genitourinary: Retrograde ejaculation (28%)
1% to 10%:
Cardiovascular: Orthostatic hypotension (3%; increased in elderly ≥65 years up to 5%)
Central nervous system: Dizziness (3%), headache (2%), insomnia (1% to 2%)
Gastrointestinal: Diarrhea (3%), abdominal pain (1% to 2%)
Genitourinary: Prostate specific antigen increased (1% to 2%)
Neuromuscular & skeletal: Weakness (1% to 2%)
Respiratory: Nasal congestion (2%), rhinorrhea (1% to 2%), sinusitis (1% to 2%)
<1%, postmarketing, and/or case reports: Hepatic insufficiency, hypersensitivity reaction, increased serum transaminases, intraoperative floppy iris syndrome, jaundice, pharyngeal edema, priapism, pruritus, purpura, skin rash (including toxic), swollen tongue, syncope, urticaria
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