There’s always a plethora of information available on practically all drug medications that are now available on the market. But has anyone really taken the trouble of tracing their beginnings, progress through time, their efficacy, the type of cases they treat, their popularity and use, combination with other drugs and so on to really come to grips with what a drug medication is all about. We will try to do this for drug medication Letrozole so just continue reading.
Letrozole beginnings and onward progress
It may be quite likely that an IPO on the stock market by the drug company Novartis was announced 1997 to mark the entry of the drug medication Femara on the market after its product was approved by the FDA, in the hope of capturing shareholder attention.
Despite the brandishing of the posh brand name, the drug was to be evermore become popular by its generic name, “Letrozole”
But what is Letrozole? Is it an anabolic steroid? No as a matter of fact, but it is closely associated with the use of anabolic steroids.
Drug family member
This chemical compound is a member of a class of drugs which are scientifically known as aromatase inhibitors or simply AI’s.
This class of drug medication has the ability of greatly reducing the effects of estrogen on the body. Initially, the drug was developed for the treatment of breast cancer in post-menopausal women but was also snatched up by bodybuilders and athletes who longed for its release for off-label usage potential.
The potent power it possessed in carrying out its anti-estrogenic mission was in fact proven genuine especially by bodybuilders who were habitually taking anabolic steroids. Why? Bodybuilders were determined to build up their testosterone levels by taking anabolic steroids.
This desire required an interaction with the enzyme aromatase which resulted in boosting up the levels of estrogen in the body, a development which bodybuilders dreaded strongly.
Letrozole is an AI and therefore works differently from Nolvadex, another anti-estrogenic drug which is not an AI but is classed as a SERM. What Nolvadex does is simply impede the estrogen receptors from binding to cancer cells but doesn’t alter the number of estrogens circulating in the body.
By contrast, Letrozole has a more dynamic action. It not only lowers the amount of estrogen circulating and renders them inactive, but at the same time it also increases the production of testosterone as well.
It’s important to note that for any taker of anabolic steroid who suffers from estrogenic side effects, any lowering of estrogen levels is a very beneficial relief.
Stacking more information on letrozole
Because letrozole has a poor ability to produce testosterone levels it’s seldom used all by itself.
Instead it can be used with at least one or more anabolic steroids which may have an estrogenic results which are not at all similar for all anabolic steroids and ins some cases, they can interact directly with the enzyme, aromatase.
Under these circumstances it could prove very beneficial to take letrozole as a precaution against the development of any unwanted side effects.
In addition, if there’s no possibility of estrogenic side effects developing such as water retention of gyno, letrozole may also be added during a cycle.
The proper way to administer letrozole
It’s possible to find Letrozole pills available but it’s only under prescription that you may be able to obtain them.
However if you choose to purchase the letrozole online you may be able to find alternative supply sources for it.
Because it’s a more common practice to purchase letrozole as a liquid, especially as a research chemical, you may find that letrozole in this form is much more widely available.
Information on Letrozole dosage
The dosage for letrozole really depends on whether or not you’re planning to make use of it as a preventive method especially if you’re aware that the appearance of estrogenic side effects has started
If you are just being cautious, you can take a smaller dose of the medication with the advice of your doctor or pharmacist.
However, if you notice that signs of gyno have started appearing, you should go for an increased dosage of letrozole after discussing your situation with your doctor or pharmacist.
The usual letrozole dose begins at 0.25mg per day and can increase up to 1mg, to be taken every other day.
Letrozole usually come in tablet form with a dose potency of 2.5mg but this would be far too potent for standard usage. The only exception would be in the treatment of gynecomastia where a 2.5mg dose taken for 7 to 14 days will eradicate any early symptoms that do appear.
Information on letrozole half-life
Letrozole has a half-life of two days which means that it won’t leave the body quickly when it’s use has been stopped. All you need to do is take your dose every other day to top-up your serum levels.
Letrozole positive effects
As far as bodybuilders are concerned, intake of letrozole will definitely help in getting rid of surplus and unwanted estrogenic side effects to leave behind a much more lean and muscle stacked body appearance.
The presence of estrogen will sometimes cause water retention and a much softer and puffy muscle appearance but letrozole can swiftly eliminate excess water and replace the vacuum bristling with leaner and rippling strong muscle formations.
Sometimes however, the problem of water retention can reach unmanageable levels where blood pressure can begin to increase, which in turn can cause other cardiovascular issues to develop if it’s not controlled properly.
Last but not least is the development of gynecomastia, a condition dreaded by bodybuilders who use anabolic steroids Gyno and can decimate the hard-won lean and tough looking muscular appearance.
Once Gyno takes hold, the only solution available would be surgery in order to reverse its effects. Gyno is caused mainly by an excess of estrogen but letrozole packs such a punch it can eliminate gyno even after it has gained a foothold.
Potential Letrozole side effects
There’s no doubting the power of letrozole and while its ability to reduce the androgenic impacts of anabolic steroidsis of immense value, it does carry some undesirable side effects of its own.
Generally speaking, these Letrozole side effects can involve fatigue and weakness, however, as long as a person is taking anabolic steroids, the potency of these side effects can be compromised.
Even so, it can become an issue for bodybuilders during intense cutting cycles, due to low intake of calories during intense training routines.
Other symptoms may include headaches, joint pains, increased blood pressure, depression and hot flashes.
Letrozole can also reduce bone mineral density but this can be normalized by increasing bone density from the use of anabolic steroids.
More serious is the one sided effect of Letrozole on cholesterol. According to studies, Letrozole can reduce HDL especially when combined with an anabolic steroid.
This has an additive as well as accumulative effect and moreover, when an anabolic steroid and Letrozole are taken together, cholesterol levels can decrease by 20%.
Bottom line
We think you’ll agree that a wealth of information has been provided for your benefit in this article. It has made available the kind of relevant information on the drug medication Letrozole on both its historical and current usage for the treatment of a wide range of conditions. One very important disclosure in the article is the very high potency of letrozole in addressing a host of conditions that affect both bodily tissue and bones.