There’s very little doubt that drug medications are increasingly becoming highly important in controlling and sometimes totally eliminating the dreaded development of estrogens in the body. To date three aromatase inhibitors (AIs) Arimidex, Letrozole and Aromasin in that order have occupied the highest echelons of the AI ladder with Letrozole a close second to Arimidex. Just simply read on for more interesting information on the Letrozole drug medication.

The primary target – controlled estrogen production

Out of the three aromatase inhibitors (AI) frontrunners in the fight against the uncontrolled production of estrogens in the body, one sure thing is happening.

 The second in line, Letrozole, has demonstrated time and time again it possesses an incredibly efficient ability in reducing estrogen in the body than the other two front runners in the group of three AI’s.

According to the current tally, Arimidex has been given top spot, Letrozole second and third Aromasin, but it appears second runner Letrozole is beginning to make an impact, although for now, we will still allot it second place.

When compared with front runner Arimidex, drug treatment Letrozole has been accorded a 10-20 times stronger placement than its peer Arimidex.

When compared to third rated contender Aromasin, although they seem to be at level par in so far as potency goes, the pathway taken by Letrozole in addressing estrogenic issues has proven highly effective in its own right.

However, it should be obvious that the use of Letrozole or any other aromatase inhibitor by an athlete or bodybuilder is somewhat different from a medical or clinical application of Letrozole or any other AI for that matter and this is what worries users of anabolic steroid.

They are concerned about three main issues as follows:

  • The proper doses for controlling estrogen production
  • How to utilize letrozole doses
  • The different ways in which Letrozole doses are administered.

Before delving into these topics, it should be known that Letrozole is an aromatase inhibitor (AI) with an extended field of applications in terms of reigning in and controlling estrogen production.

Because it is an AI, this drug medication has the ability to hold sway over literally all of the side effects that the presence of estrogen can make manifest and against which users of anabolic steroids are constantly at pains in avoiding or in totally eliminating.

It should therefore be obvious that a general rule should be devised for regulating the use of all AI’s such as by using the underlying principle shown below:

An attempt should be made not to use AI’s at all costs unless absolutely necessary. If it’s found that using an AI is deemed necessary, utilize it only when needed, using the lowest possible does should be attempted for the purpose of Estrogen control rather than Estrogen elimination.

The above is critically important and must be recalled to mind by all readers who investigate the use of aromatase inhibitors (AI’s).

The truth of the matter is that when the three aromatase inhibitors (Arimidex, Letrozole and Aromasin) are used or any other AI for that matter, will have the potential of exerting a negative impact on the body when they are not needed or when they are overused or the doses are way too high.

It should always be kept in mind that the main reason for the taking of an aromatase inhibitor (AI) should exclusively for controlling the level of estrogen circulating in the body and certainly not for eliminating estrogen from the body.

The reason is simple. If all estrogen is totally absent from the body by virtue of being removed one way or another, the result would result in harmful consequences to the human body. This will be seen in clearer light when the side effects of letrozole are addressed later.

For now, it’s important to note that these aromatase inhibitor compounds actually deprive the body of a very beneficial hormone i.e. estrogen, which is critically important for essential functions in the body.

Dosage for Letrozole when taking anabolic steroid

Strictly speaking it’s not possible to categorize aromatase inhibitor Letrozole in line with the different users for example by as beginner, intermediate and advanced users as is normally the case for users of drug medication compounds.

The reason is that Letrozole in used in a purely supportive role as for instance it doesn’t enhance performance but instead is used for combating or mitigating the different Estrogenic side effects when athletes or bodybuilders use aromatizable anabolic steroids.

The endogenous secretion of testosterone in men may also be generated by taking letrozole doses when the compound is available for use as an ancillary medication during post cycle therapy (PCT) especially at the end of an anabolic steroid cycle.

However it’s not very commonly used on its own for enhancing athletic performance or for gaining lean muscle mass. Its key role as a stimulating agent for endogenous Testosterone will soon be discussed in detail, below.

Letrozole is the most efficacious aromatase inhibitor that’s used for reducing levels of circulating estrogen in the body during a cycle that involves the use of androgens that can be amortized and can be converted into estrogen.

In addition to what has been discussed above, the range of Letrozole doses stand at approximately 1.25mg – 2.5mg per day.

Too much or too little for Letrozole dosages?

Referring specifically to Letrozole dosages, a big margin for adjustment to user preferences exists. This is so because each individual will definitely see the need to adjust to the doses they’ve been given and the way they feel their bodies responding to the doses.

This is especially so for Letrozole which has been recognized as the most potent and powerful AI of the three front line AI’s, and the reason why even a 1.25mg daily dose is considered too high even for many users of steroids.

Quite often, the dose is tapered down to  1.25mg every other day or once every two days and can even be reduced further especially in view of the half-life of Letrozole which is 2 – 4 days.

The good news is that the Letrozole doses can be easily adjusted if it’s not working well for the user and this is why it’s important to always remember that the original purpose for using AI’s is for controlling the level of Estrogen levels to be as normal as possible.

The story seems to be different when letrozole is used for the treatment of gynecomastia where it has now been proven beyond any doubt that the drug medication is capable of reversing and totally eliminate the growth progress of gynecomastia.

So the essential difference between Letrozole and the rest of the other AI’s is that for the other AI’s do not have the ability to reverse the progression and total elimination of cancer cells in the breast.

They can only offer treatment up to the irreversible point from where surgery can only be the only option available for getting rid of the cancer.

As already discussed, for Letrozole, the outlook is less bleak as it has the ability to reverse and eliminate the progression of gynecomastia.

Bottom line

Whenever the word ‘cancer’ is hollered, there’s always that apprehensible feeling that it’s there and it there it will stay wherever that may be. It used to be a very disconcerting and unnerving word to hear and sympathy usually went out to the person who was suffering from such a fate. Fortunately those days are gone since with the appearance of Letrozole, it’s possible to reverse cancerous growth to the point where it can no longer overreach itself.